A purification method in which nucleic acids bind to paramagnetic beads and are collected with a magnet through wash steps. It automates well, which is why most high-throughput extraction platforms are bead-based; compare deck footprint and sample capacity when shortlisting systems.
Extraction MethodologyIVD Knowledge Base
IVD & Molecular Diagnostics Glossary
A comprehensive glossary of in vitro diagnostics (IVD) and molecular diagnostics terminology, covering PCR terms, extraction methodology, regulatory definitions, and performance metrics.
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N
The sample-preparation stage that lyses cells or virions and purifies DNA/RNA before amplification. Extraction quality (yield, purity, inhibitors removed) often limits assay performance more than the PCR itself, and it defines required instruments and hands-on time in a workflow.
Extraction MethodologyP
An enzymatic pre-treatment in nucleic-acid extraction that degrades proteins and nucleases, releasing nucleic acids from clinical material before binding, wash, and elution steps.
Extraction MethodologyS
A purification method that binds nucleic acids to a silica membrane in a spin column through centrifugation or vacuum. It is a common manual and mid-throughput format with well-understood consumable logistics, but is less automation-friendly than magnetic bead approaches.
Extraction Methodology