Test guide

Hepatitis B Virus DNA Quantification

Quantifies hepatitis B virus DNA to guide treatment decisions and monitor response.

For everyone & professionals

What it is for

Determines replication activity alongside HBsAg, HBeAg and ALT; identifies candidates for antiviral therapy per WHO and AASLD thresholds, monitors virologic response to nucleos(t)ide analogues, and assesses risk in pregnancy to guide neonatal prophylaxis.

Limitations

Viral load must be interpreted together with serology and liver function; a single value does not distinguish phases of infection. Assays differ in linear range at the low end.

Before you test

For individuals: a standard blood draw is required. Bring prior results if available so your clinician can compare trends.

Health information only. This guide does not diagnose or replace advice from a healthcare professional.

Also known as

  • HBV DNA
  • HBV viral load

Reviewed products

Editor-curated products linked to this test. Verification status and sources are shown on each product page.

cobas® HBV

Roche Diagnostics · verified 2026-10-04

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cobas® HBV (cobas® 4800)

Roche Diagnostics · verified 2026-10-04

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